Pradaxa 150mg

Brand Choice
Product from Canada

Pradaxa 150mg

Manufactured by: Boehringer Ingleheim

 
From $2.50 USD/Capsule(s)
 

CAN NOT BE SPLIT Must be taken in existing form.

PRESCRIPTION REQUIRED

 
Generic Equivalent
Product from Canada

Dabigatran 150mg

 
From $2.17 USD/Capsule(s)
 

CAN NOT BE SPLIT Must be taken in existing form.

PRESCRIPTION REQUIRED

What is a Generic in Canada? Health Canada (the Canadian regulatory board) evaluates every Canadian generic for their safety, effectiveness, and quality. Every generic used in Canada has the same medical ingredients as their brand name counterpart and is considered bioequivalent to the brand name medication. The quality standards for brand name drugs and generic drugs are the same. All of the ingredients, facilities, and manufacturing processes must meet Canadian federal guidelines for Good Manufacturing Practices. In addition, Canadian generic manufacturers must perform 'comparative bioavailability' studies to demonstrate that their generic products deliver the same amount of medicinal ingredient at the same rate as the brand name medication. Nearly 45% of all prescriptions filled in Canada use generic medication and some hospitals exclusively use generic drugs. For more information, please visit  http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/med-gen-eng.php

Pradaxa 150mg

Strengths available

Brand name

Pradaxa (pronounced as pra-DAX-ah)

Generic name

Dabigatran (pronounced as Dah-BIG-ah-tran)

Manufacturer Information

Boehringer Ingelheim

 

About Pradaxa 150mg

What type of drug is Pradaxa?

The active ingredient in Pradaxa is Dabigatran Etexilate. Pradaxa belongs in the drug class called anticoagulant - commonly known as blood thinners. Pradaxa indications include prevention of VTE (venous thromboembolic events) in patients who had hip replacement or knee replacement surgery, treatment and prevention of DVT (deep vein thrombosis) and pulmonary embolism, and the prevention of strokes/embolisms in patients with afib (atrial fibrillation).

How does Pradaxa work?

Pradaxa (Dabigatran) is a reversible direct thrombin inhibitor which prevents the conversion of fibrinogen to fibrin and thus prevents the development of thrombus. The half-life of Pradaxa is about 12-14 hours and is independent of dose.

The bioavailability of Pradaxa is greatly increased when the pellets are taken without the outer capsule shell - therefore, to avoid this, Pradaxa should always be taken whole. Do not open the capsules and take the pellets alone or sprinkled over food/into beverages.

Pradaxa Dosage directions

Speak to your doctor about your kidney functions before starting Pradaxa as dosage adjustments will be required if you have renal impairment. In general, if you're using Pradaxa post-surgery, therapy should start 1-4 hours after the surgery is completed. The maintenance dose for knee or hip replacement surgery is 220mg daily for 10 to 35 days. For treatment or prevention of DVT and PE, doses can vary from 110mg twice daily to 150mg twice daily.

If you forget and miss your dose, do not double dose to make up for the missed dose. In most cases, you can take a dose of Pradaxa up to 6 hours prior to your next scheduled dose or continue with regularly scheduled doses. Depending on what you're using Pradaxa for, the pharmacist will have different advice.

Are there Alternatives to Pradaxa?

Alternatives to Pradaxa include Plavix, Eliquis, Xarelto, and Coumadin.

To clear the air, "Plavix" is an "anti-platelet agent" while the other drugs in the list are "blood thinners". This technicality affects prescriber choice far more than patient choice. For patients who do not want to get into the technicalities, just know that they're not the same thing and they're not interchangeable.

The differences between Pradaxa, Eliquis, and Xarelto are much less distinct. These agents are classified as new direct anticoagulants. Studies have shown that new direct anticoagulants work just as well as Coumadin (warfarin) but comparing these agents head to head is a much more difficult task. Other than considering the specific indication, and whether current medical studies show any safety or efficacy benefit between the three choices, a lot of the patient/prescriber choice boils down to individual patient lifestyles and health conditions. For example, for non-compliant patients, prescribers may consider Xarelto which is dosed once daily versus the twice daily requirement of Eliquis and Pradaxa. Pradaxa is known for causing more stomach upset and is more affected by poor renal function so if a patient gets nauseous easily, it may not be the best choice. Eliquis can cause more gastric bleeding than the other drugs so avoid in patients who are already at increased risk. Overall, these new direct anticoagulants are increasingly popular because of their low need for regular lab monitoring compared to the old-school-gold-standard, warfarin. Although warfarin requires regular (usually once/month) lab tests, it still has a place in modern anticoagulant therapy for patients who have severe liver or kidney dysfunction.

Pradaxa Side-Effects

The majority of Pradaxa side effects are related to signs of bruising or bleeding. On rare cases, it can cause serious or severe bleeding and if that occurs at any part of your body, seek immediate medical attention. For this reason, if you fall, hit your head, or injure yourself in any other way, please seek immediate medical attention. Please refer to your patient insert provided with your Pradaxa for a full list of possible side effects.

Should I take Pradaxa with or without food?

Pradaxa can be taken on an empty stomach or with food.

Does alcohol interact with Pradaxa?

There is no direct interaction between Pradaxa and alcohol but drinking regularly may increase your risk of stomach bleeding. Please talk to your doctor to find out how much alcohol is safe for you.

Taking Pradaxa when Nursing

There are no data available to support the use of Pradaxa while nursing. As a result, please talk to your doctor about either discontinuing nursing or discontinuing the drug.

 

Buying Pradaxa 150 mg Online from Canada

Pharmacies in USA may charge over $400 for a month's supply of Pradaxa and get away with it because Pradaxa has so much positive patient review. By ordering from Canada Cloud Pharmacy, you can save up over half of your Pradaxa costs.

Give us a call to chat with our pharmacists to find out how to order online and delivery options available. Although you won't be able to use your local discount cards or savings card, you can still save on your medication, even if you have a copay, when you buy from a licenced Canadian Pharmacy.

 

FAQs

Does Pradaxa affect my INR?
No. Although Pradaxa will affect your INR, you are not required to go for monthly INR lab testing as you would with warfarin.
When will Pradaxa patent expire?
The patent is due to expire in USA in 2023. The patent for Pradaxa has expired in Canada already meaning there now is a Canadian generic available for Pradaxa.
What do I do if I'm taking Pradaxa and I'm going for surgery?
Generally, patients are advised to stop their Pradaxa at least 24 hours prior to surgery. However, your physician may advise you to stop your Pradaxa well prior to that - please speak with your doctor and assess each case individually.
Can I open or crush Pradaxa capsules?
No. Do not crush Pradaxa or open the capsules to sprinkle the pellets in food/drink.
What do I do if I want to try a new blood thinner?
There is a protocol for switching between Pradaxa and all other anticoagulants. Please speak with your doctor or find out more information at the link below: https://www.pharmacytimes.com/contributor/beth-lofgren-pharmd-bcps/2015/01/how-to-convert-between-anticoagulants
Can I open the Pradaxa capsules if I find it difficult to swallow Pradaxa capsules?
Pradaxa capsules can not be opened as when they are opening and the contents removed from the hard shell it can dramatically effect how the drug is absorbed in the body. If you are having difficultly taking the medication always speak with your Doctor. Do not open Pradaxa capsules.

 

 

Buy Pradaxa 150mg from Canada 

Information contained here on this page is for informational purpose only. Always speak with your Doctor about the usage of your medication. 

 

Canada Cloud Pharmacy are members of the following programs.

College of Pharmacists
 

Information available on this website is for informational purposes only and should not be relied upon as specific advice for you. Do not rely on the information without seeking advice from a professional. You should not use the information contained on this website for diagnosis, treating, or preventing health problem. Always consult your own physician for advice and treatment.

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