Jublia (Efinaconazole) 10%
10% topical solution
Jublia (pronounced as JUBE-lee-ah)
Efinaconazole (pronounced as ef-fee-nah-CON-ah-zole)
What is Jublia?
Jublia, which contains the active ingredient efinaconazole, is a topical solution that is indicated for the topical treatment of mild to moderate onychomycosis on toenails for adults.
How does Jublia work?
Jublia contains Efinaconazole, an antifungal belonging to the azole group. It applies it's antifungal properties by acting to inhibit the fungal lanosterol 14α-demethylase which is essential in the biosynthesis of ergosterol. Without egosterol the cell membrane of the fungi looses it's integrity and breaksdown killing the fungi.
Jublia has low systemic absorption so most of its fungicidal and fungistatic activity is topical. A benefit of having low systemic absorption means that Jublia is well tolerated and has minimal side effects and no known drug interactions.
The downside of this mechanism of action is that it takes several months to clear the infection - although this is also partly due to how long it takes new, healthy, nail to grow and replace the old infected nails.
How to apply Jublia
Hold the bottle upside down and gently squeeze the bottle to wet the brush.
Apply 1 drop of Jublia to affected nail, or 2 drops if applying to the big toenail. Use the applicator brush to spread the solution.
Repeat these steps to apply to all affected toenails and let the area dry. Wash your hands with soap at the end of these steps.
Try to not miss any doses but if you do, apply your dose as soon as possible.
If you forgot your dose and it's almost time for the net dose, skip the missed dose and return to your usual scheduled doses.
Jublia reviews and efficacy.
Multiple clinical trials have shown that 48-52 weeks of therapy with Jublia is effective for eliminating nail fungus and allow new, clear, nail to grow back. Due to its long therapy, patient reviews tend to be mixed - patients who are compliant and soldier through therapy tend to have positive reviews, especially for patients who have tried other over the counter options (such as tea tree oil, or filing down nails) and failed to notice improvements previously.
Patients who discontinue therapy too early may not notice any changes as it takes several months for new nail growth to be noticeable.
Side effects of Jublia
Jublia is generally well tolerated and the most common side effects are local skin irritation (ex. burning) in the area bordering the nails.
On rare occasions, you may experience a blister on your skin near the application site or your affected nail may become ingrown. Please talk to your doctor if that happens.
Is there a generic available for Jublia?
Unfortunately, there is Jublia generic available currently.
When will a Jublia generic be available?
According to Drug Patent Watch, the patent of Jublia is due to expire in 2021. This means we could expect a Jublia generic within the next few years and as early as 2021, providing another generic company manufacturers.
Can I drink alcohol when using Jublia?
One advantage of choosing Jublia over oral antifungal therapy is that Jublia does not have any interactions with alcohol.
When should I use oral antifungals instead of Jublila?
Oral antifungals, such as Lamisil or Sporanox, can clear infections quicker (approx. 6-12 weeks) but, like Jublia, you will not notice results until the nail grows back completely which may take over 4 months.
You should keep in mind that oral antifungal medication have more side effects and drug interactions and, depending on your health, your doctor may ask you to go for blood tests. Oral antifungals are your best chance of resolving a severe nail infection but due to potentially dangerous side effects, are not commonly recommended for fungal nail infections unless the infection is severe or if a patient failed to improve using topical methods. Additionally, there is evidence that oral antifungal therapy may be less effective for patients over 65 years old.
Ordering brand name Jublia from Canada
Don't compromise on your safety or treatment because of high drug prices of Jublia in America. Buy the brand name Jublia your doctor chose for you direct from Canada and have it delivered to your home. Avoid the hassle of patient assistance programs and copays when you order Jublia online from Canada Cloud Pharmacy.
Buying Jublia from your local pharmacy may cost $600-$700 for a small 4ML bottle. When there is no Jublia manufacturer coupon available, the cost of Jublia can be mitgated by ordering name-brand Jublia from Canada Cloud Pharmacy.
Buy Jublia from Canada
Information contained here on this page is for informational purpose only. Always speak with your Doctor about the usage of your medication.