What is a Generic in Canada? Health Canada (the Canadian regulatory board) evaluates every Canadian generic for their safety, effectiveness, and quality. Every generic used in Canada has the same medical ingredients as their brand name counterpart and is considered bioequivalent to the brand name medication. The quality standards for brand name drugs and generic drugs are the same. All of the ingredients, facilities, and manufacturing processes must meet Canadian federal guidelines for Good Manufacturing Practices. In addition, Canadian generic manufacturers must perform 'comparative bioavailability' studies to demonstrate that their generic products deliver the same amount of medicinal ingredient at the same rate as the brand name medication. Nearly 45% of all prescriptions filled in Canada use generic medication and some hospitals exclusively use generic drugs. For more information, please visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/med-gen-eng.php
Motegrity 1 mg
Motegrity (US) (pronounced as Mo-teg-rit-tee)
Prucalopride (pronounced as Prew-cal-oh-pride)
About Motegrity 1 mg
What type of medication is Motegrity?
Motegrity or as it is known in Canada, Resotran, is a prokinetic medication used for the treatment of chronic idiopathic constipation where laxatives have been inadequately effective. The active ingredient, chemical name is prucalopride. Prucalopride belongs to a class of compounds known as dihydrobenzofurancarboxamide. Prucalopride is marketed under three different brand names namely Resolor (US), Resotran (Canada) and Motegrity (US).
How does Motegrity (Prucalopride), work?
As a prokinetic medication, Motegrity works to stimulate peristalsis and the movement along the alimentary canal to alleviate symptoms of chronic constipation. As a serotonin 5-HT4 receptor agonist, prucalopride stimulates proximal colonic movement and increases the rate of gastric emptying. These effects serve to regulate bowel movements and decrease the symptoms of chronic constipation.
How should I take Motegrity?
The recommended dosage of Motegrity is 2mg once daily. Doses are frequently commenced on a lower dosage and titrated up to the maximum recommended dosage of 2mg. If there are no bowel movement in 3-4 days additional, adjunct laxatives should be considered.
If you miss a dose of your Motegrity take the dose as soon as you remember and then take your next dose approximately 24 hours later. DO NOT double your dose if you miss a dose as Motegrity has a long half-life of around one day.
Motegrity (Prucalopride) as an adjunct treatment and remission of SIBO (Small Intestinal Bacterial Overgrowth)
One of the main causes for SIBO (Small Intestinal Bacterial Overgrowth) is an underlaying impaired motility. For many years Doctors have been using prokinetics in an attempt to normalize bowel movements and prevent SIBO relapse. Some Doctors prescribe prucalopride, off-license for this purpose.
What side-effects could I expect when taking Motegrity?
The most common side effects of Motegrity include, but are not limited to; Gastrointestinal side-effects - due to the mechanism of action of Motegrity some patients may suffer from nausea or diarrhea. Other side-effects include headache as well as dizziness.
Should I take Motegrity with food?
Motegrity has no reported interactions to food and for this reason may be taken with or without food. The important thing is to try to take resolor at the same time each day, so doses are taken 24 hours apart.
Is it safe to drink alcohol when taking Motegrity?
There are no drug-drug interactions reported between alcohol and Resolor. However, as Resolor may cause dizziness this may be exacerbated by alcohol.
Are there any drug-drug interactions to be aware of when taking Motegrity?
Always inform your Pharmacist ad Doctor of all medication you are taking at the time of dispensing. Motegrity (Prucalopride) interacts with P-gp inhibitors such as Ketoconazole, Verapamil, Cyclosporine A and Quinidine. This list is not complete so always check with your Pharmacist with the medication you are taking.
How to buy Motegrity online from Canada?
Many Doctors in the US advise their patients to attain Motegrity in Canada where it is widely available and more affordable. Canadian Pharmacies, such as ourselves, Canada Cloud Pharmacy, have been helping patients for years source their resolor medication.
Whether you are ordering online or picking up in store, Canada Cloud Pharmacy are here to answer all your questions and provide you with expert advice on your medication. Your medication can be delivered direct to your door using one of three shipping option, chosen when checking out.
Can I use other laxatives whilst taking Motegrity?
If there has been no bowel movements for three to four days, rescue laxatives, are often recommended to be used in combination with Motegrity. Each patient is unique in terms of their normal bowel movements so please ensure you speak with your Doctor before using laxatives when taking Motegrity.
Is Motegrity called Resotran in Canada? Is Motegrity and Resotran the same thing? Motegrity vs Resolor?
I know how confusing this can be. Prucalopride, the chemical name for Motegrity, is marketed under three different brand names. Resolor was the original brand name marketed in USA, whilst in Canada it was marketed under Resotran. Most recently, Motegrity has been marketed in the US for prucalopride. They are all the same medication, so whether your prescription states Resolor or Motegrity you will receive Resotran from Canada.
What are the alternatives to Motegrity?
Alternatives to Motegrity would include other prokinetic medication. You should discuss with your Doctor different options but some examples of other potential alternatives to Motegrity include domperidone, erythromycin, linzess and metoclopramide.
Is Resotran available in USA?
No. Resotran is the marketed name for prucalopride in Canada approved by Health Canada. Two brand names have been marketed in the US for prucalopride and approved by the FDA, they are Resolor and Motegrity.
How to order Motegrity in Canada?
If you would like to order Motegrity in Canada you will need a prescription from a licensed Doctor. Select the quantity you need and add to cart above. Select the cart symbol and the top right hand corner of the screen and click the big blue checkout button to proceed. Please note, Motegrity is called Resotran in Canada. You will always have an opportunity to speak with a pharmacist when placing an order.
Buy Motegrity 1 mg from Canada
Information contained here on this page is for informational purpose only. Always speak with your Doctor about the usage of your medication.