Restasis 0.05%

Brand Choice
Product from Canada

Restasis 0.05%

Manufactured by: Allergan

 
From $5.00 USD/vials
 

CAN NOT BE SPLIT Must be taken in existing form.

PRESCRIPTION REQUIRED

 
Generic Equivalent
Product from Canada

Cyclosporine 0.05%

 
From $3.00 USD/vials
 

CAN NOT BE SPLIT Must be taken in existing form.

PRESCRIPTION REQUIRED

What is a Generic in Canada? Health Canada (the Canadian regulatory board) evaluates every Canadian generic for their safety, effectiveness, and quality. Every generic used in Canada has the same medical ingredients as their brand name counterpart and is considered bioequivalent to the brand name medication. The quality standards for brand name drugs and generic drugs are the same. All of the ingredients, facilities, and manufacturing processes must meet Canadian federal guidelines for Good Manufacturing Practices. In addition, Canadian generic manufacturers must perform 'comparative bioavailability' studies to demonstrate that their generic products deliver the same amount of medicinal ingredient at the same rate as the brand name medication. Nearly 45% of all prescriptions filled in Canada use generic medication and some hospitals exclusively use generic drugs. For more information, please visit  http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/med-gen-eng.php

Restasis

Strengths available

0.05%

Brand name

Restasis (pronounced as reh-STAY-sis)

Generic name

Cyclosporine (pronounced as psy-clo-SPORE-rin)

Brand Manufacturer Information

Allergan

 

About Restasis

What is Restasis?

Restasis, which contains the active ingredient cyclosporine, is an eye drop that is used to increase tear production to help patients whose eyes do not naturally produce enough tears to prevent eye irritation.

How does Restasis work?

The exact mechanism of Restasis is unknown but likely to act as an immunosuppressant that decreases inflammation in tear glands. Over time, decreasing inflammation can help patients recover tear production and to stop the damage that inflammation causes to their tear glands. This process can weeks to up to 6 months for maximum benefit. Because of this delayed onset, your doctor may also prescribe other eyedrops to help with discomfort.

How do I use Restasis?

Restasis is usually given 1 drop, in each eye, twice daily. To administer the drop, invert the vial a few times until the white emulsion is uniformly opaque. Avoid touching the tip of the vial it your eyes or any other surface and discard the single-use vial immediately after using it in both eyes to avoid contamination.

If you wear contacts, remove them before applying Restasis - you may reinsert them 15 minutes after administration. If you're using any other eyedrops, such as artificial tears, wait 15 minutes before applying the next product.

If you forget a dose, take it as soon as you remember. But if it's almost time for the next dose, skip the missed dose and resume your regular dosing schedule (i.e. do not double your dose)

Off label uses for Restasis

Off-label, or unofficial, use is when medications are used for an unapproved indication and it is common for both prescription medication and over-the-counter medication to have off-label uses. Because of its immunosuppressive properties, Restasis is used off-label to quickly treat uveitis. Unlike topical cortical steroids which may take weeks to show improvement for uveitis patients, the effects of Restasis can be observed within days and it is used as a steroid-sparing agent. Decreasing the dose of steroids is especially important in younger patient populations as steroid use is linked with an increased likelihood of developing or worsening glaucoma.

Another common off-label use for Restasis is to prevent and treat post-LASIK dry eye. Some specialists will also pre-treat LASIK patients with Restasis to improve the symptoms of dry eyes after surgery and to reduce glare/halo post-surgery. Restasis is also used to manage allergic-type conditions. For example, patients with atopic dermatitis or eczema may experience inflammation in their cornea and Restasis is used to help manage that. Similarly, Restasis is used after corneal transplant to prevent rejections.

What are the common side effects of using Restasis?

The most common Restasis side effect is a burning sensation when applying the drops. Other common side effects include headache, redness, eye discharge, eye pruritis, blurred vision, and foreign body sensation. As your eyes get more accustomed to using Restasis, these symptoms usually improve. If you experience any swelling, shortness of breath, or a skin rash, then you may be allergic to Restasis.

If you’re allergic to Restasis, discontinue the drug immediately and speak with your doctor.

Is Restasis multidose?

Restasis comes in two different formulations and both are preservative free. Most commonly Restasis is packaged in preservative-free single-use vials. The multi-dose unit keeps the medication microbe free and safe to use by way of clever bottle design that protects the liquid inside.

Restasis vs Xiidra

Xiidra and Restasis work at different points of the inflammation cycle. Xiidra works much earlier in the cycle and, as a result, patients experience benefits from Xiidra quicker than they do with Restasis. It may take Restasis patients up to 16 weeks to experience symptom improvement whereas Xiidra patients experience improvements in 6-12 weeks, sometimes as quickly as 2 weeks. If you wear contact lenses, your doctor may choose Xiidra as you may insert your lens 15 minutes after instilling your eye drops (contact lens are not recommended for Restasis patients). Even though burning and stinging is commonly reported with Xiidra use, it is even more commonly reported with Restasis use.

What drugs interact with Restasis?

Xiidra and Restasis work at different points of the inflammation cycle. Xiidra works much earlier in the cycle and, as a result, patients experience benefits from Xiidra quicker than they do with Restasis. It may take Restasis patients up to 16 weeks to experience symptom improvement whereas Xiidra patients experience improvements in 6-12 weeks, sometimes as quickly as 2 weeks. If you wear contact lenses, your doctor may choose Xiidra as you may insert your lens 15 minutes after instilling your eye drops (contact lens are not recommended for Restasis patients). Even though burning and stinging is commonly reported with Xiidra use, it is even more commonly reported with Restasis use. Xiidra is an alternative to Restasis.

 

How to order Restasis from Canada

A carton of Restasis can cost $500-$600 in USA and is prohibitively expensive for most patients. Here's where Canada Cloud Pharmacy can help. Canada Cloud Pharmacy is a licensed, brick-and-mortar pharmacy that’s been serving the local community for over 6 years. At Canada Cloud pharmacy, USA and international patients can order online, have medication delivered to their door, and enjoy Canadian drug prices. Whether you have a Restasis coupon, a savings card, or a patient assistance program, make sure to check prices online as you can still save with Canadian prices.

Canada Cloud Pharmacy only sends medication from Canada and we offer the same medication online as we do to our local in-store patients. Order Restasis online and have it delivered to your door in 5 days. Save on Restasis and other medication now by speaking with a real pharmacist today.

 

FAQs

Is there a Restasis generic available?
Yes. A newly available Restasis generic was released in the Canadian market in 2019. There is still no generic for Restasis in the US.
What ingredients are in Restasis?
Restasis contains cyclosporine 0.05% w/v in single-use vials. Non-medical ingredients include: Carbomer Copolymer Type A, castor oil, glycerin, polysorbate 80, purified water and sodium hydroxide
Why is Restasis not approved elsewhere?
Restasis is not approved in the EU, Australia, or in New Zealand because it was unable to provide sufficient evidence of efficacy for its official indications. Even though Restasis is approved in Canada, our provincial and federal drug plans do not currently pay for the medication because medical boards are not convinced of meaningful benefit.
Does Restasis cause hair loss?
No, Restasis has not been shown to cause hair loss. There is on-going research to determine if Restasis' immunosuppressive properties may promote hair growth.
Is Restasis safe? Does Restasis cause cancer?
In general, immunosuppression is a risk factor for cancer. Many studies examine the use of systemic cyclosporine and extrapolate the risk to ophthalmic settings. Topical cyclosporine absorption is negligible and experts expect that a topical/local administration would have a low risk of systemic tumor development. However, there is a concern of long term cyclosporine use within the ophthalmic community.
When will a Restasis generic be available?
The patent for Restasis has already expired here in Canada and in the States. The generic is already on the market here in Canada but what's going on in the States? It seems generic drug makers are still awaiting the go ahead from the FDA on the approval of the generic version. Until then, US patients are sticking with Canada for their Restasis brand and generic.

 

 

Buy Restasis from Canada 

Information contained here on this page is for informational purpose only. Always speak with your Doctor about the usage of your medication. 

 

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College of Pharmacists
 

Information available on this website is for informational purposes only and should not be relied upon as specific advice for you. Do not rely on the information without seeking advice from a professional. You should not use the information contained on this website for diagnosis, treating, or preventing health problem. Always consult your own physician for advice and treatment.

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