Trelegy Ellipta Inhaler 100/62.5/25MCG

Brand Choice
Product from Canada

Trelegy Ellipta Inhaler 100/62.5/25MCG

Manufactured by: GLAXO SMITHKLINE

One Inhaler(s) contains 30 Doses

From $164.99 USD per Inhaler(s) (click)

CAN NOT BE SPLIT Must be taken in existing form.


Generic Choice
Product from Canada

No Generic Alternative Available

No generic alternative is available for this drug.


Strengths available

Fluticasone 100 mcg, Umeclidinium 62.5 mcg and Vilanterol 25 mcg

Brand name

Trelegy Ellipta (pronounced as tray-low-gee)

Generic name

Manufacturer Information
GlaxoSmithKline (GSK) 

About Trelegy Ellipta 

What is Trelegy Ellipta Inhaler?

Trelegy Ellipta is a FDA-approved once-daily inhaler medicine that combines 3 long-acting medicines in 1 inhaler and is used to treat and manage lung functions in chronic obstructive pulmonary disease (COPD) in adults. Trelegy Ellipta is effective for reducing flare-ups. Trelegy Ellipta is a maintenance medication and cannot be used to relieve sudden breathing problems.  Trelegy Ellipta is not for the treatment of asthma.

How does Trelegy Ellipta work?

This inhaler delivers three drugs namely, fluticasone furoate, umeclidinium, and vilanterol. 
Fluticasone is an anti-inflammatory corticosteroid. Fluticasone helps to decrease inflammatory cells,  such as eosinophils, monocytes, mast cells, macrophages, and dendritic cells. It reduces inflammation and swelling in the lungs. 
Umeclidinium is a long acting antimuscarinic (LAMA) anticholinergic that affects muscarinic receptors M1 - M5.  Umeclidinium causes bronchodilation in the airways by inhibiting the M3 receptors at the smooth muscle sites. It blocks tightening of smooth muscle around your airways and keep them open. 
Vilanterol is a long acting bronchodilator (LABA). It increase cyclic AMP levels, relaxes bronchial smooth muscles, and inhibits inflammatory mediators. It opens airways by relaxing muscles around the airways in your lungs and thus ease the breathing.

What is the most common dosage of Trelegy Ellipta?

Use 1 inhalation a day. Try to use medication at the same time every day. If you miss a dose of inhalation, take it immediately whenever you remember. Do not exceed 1 inhalation per day. Take your next dose at your usual time. Do not take 2 doses at 1 time. That means 1 single inhalation once a day will provide you a full 1 day of easy breathing. This inhaler reduces COPD flare-ups. 
Your symptoms may worsen if you discontinue your inhaler without speaking to your healthcare provider. Just remember that if you stop taking your daily dose by inhalation, symptoms could return. Your healthcare provider will change your medicines as needed.

Directions on using your Trelegy Ellipta inhaler

Always follow the instructions that come with the inhaler. Before the inhaler is used for the first time, the counter will show the number 30, which represents the number of doses packed in the inhaler. If you just open and close the cover without inhaling the medicine, your 1 dose is lost. The lost dose will be trapped inside, but won’t be available for inhalation.  
Open the cover of the inhaler and slide the cover down to expose the mouthpiece. You should hear a “click.” The counter will count down by 1 number. Do not shake the inhaler. If the counter does not decrease by 1 number, means inhaler will not deliver the medicine. 

Exhale fully while holding the inhaler away from your mouth. Do not breathe out into the mouthpiece. Close the mouthpiece between the lips so as to fit it perfectly over the curved shape.  
Take one breath in through your mouth. Do not block the air vent with your fingers. Remove the inhaler from your mouth and hold your breath for about 3 to 4 seconds.
Breathe out slowly and gently. You may not taste or feel the medicine, even when you are using the inhaler correctly.  Close the inhaler. If you need to clean your mouth piece, use a dry tissue.  Rinse your mouth with water and spit the water out, without swallowing it.  

When should you get a refill of Trelegy Ellipta?

When you have less than 10 doses in the inhaler, red indicator as a reminder will be seen. This is the time to get it filled. After inhalation of the last dose, the counter will show “0” and the device will be empty. Throw away the empty inhaler device away in your household trash. Keep the inhaler out of reach of children and pets.
What are the side effects of Trelegy Ellipta?

Common side effects of this inhaler are upper respiratory tract infection, pneumonia, bronchitis, thrush in your mouth and throat, headache, back pain, joint pain, flu, inflammation of the sinuses, runny nose and sore throat, taste disturbance, constipation, cough and hoarseness. It can cause serious side effects, fungal infection in your mouth or throat. People with COPD have a higher chance of getting pneumonia. This inhalation therapy may increase the tendency of getting pneumonia. You may notice symptoms like increase in sputum production, change in mucus color, fever, chills and weakened immune system and increased chance of getting infections.  
Eye problems may occur like glaucoma, increased pressure in your eye, cataracts, blurred vision, worsening of narrow-angle glaucoma, or other changes in vision.  
You may experience reduced adrenal function and may feel tired, lack of energy, weakness, nausea and vomiting, low blood pressure due to adrenal insufficiency. 
People who take this inhaler may develop new or worse urinary retention. Symptoms of urinary retention are difficult and painful urination, frequent urination and in a weak stream or drips.

Buying Trelegy Ellipta in Canada with an American prescription

With the ever increasing cost of this medication in the States, more and more patients are coming to Canada to buy their medication.  By ordering online from a Canadian Pharmacy such as ourselves, ( patients have been able to save thousands of dollars per year for an equivalent, safe and effective option.


How much does Trelegy Ellipta cost?

The cost can vary depending on prescription dosage and length of treatment. Generic alternative is not yet available. COPD patients can buy online from a mail-order pharmacy such as to help manage high medication costs.

Is there a generic for Trelegy Ellipta?

A generic for Trelegy Ellipta is not available in Canada.

How do I store Trelegy Ellipta?

Store the inhaler at room temperature between 68°F and 77°F (20°C and 25°C) in a dry, dark place. If you store in a refrigerator, allow the inhaler to return to room temperature for at least an hour before use. It’s a good idea to note the date you open the tray on the label on the inhaler.

Can I smoke when using my Trelegy Ellipta Inhaler?

Stopping smoking will help to decrease your COPD symptoms. Please speak to your Doctor about quitting today.

What should I do if I missed my daily dose of Trelegy Ellipta?

If you miss a dose, take your next dose at the usual time the next day. Do not take extra dose to make up for the missed one. 
Information contained here on this page is for informational purpose only. Always speak with your healthcare provider about the usage of your medication. 


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College of Pharmacists

Information available on this website is for informational purposes only and should not be relied upon as specific advice for you. Do not rely on the information without seeking advice from a professional. You should not use the information contained on this website for diagnosis, treating, or preventing health problem. Always consult your own physician for advice and treatment.

All prices are subject to change at any time. Please contact us for questions regarding pricing and availability of products.



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