Xifaxan (Rifaximin) 550 Mg
Product from Canada
Manufactured by: Lupin Pharma
Marketed as: Zaxine in Canada
From $10.41 USD per tablets(s)
CAN NOT BE SPLIT Must be taken in existing form.
Product from Canada
No Generic Alternative Available
No generic alternative is available for this drug.
What is a Generic in Canada? Health Canada (the Canadian regulatory board) evaluates every Canadian generic for their safety, effectiveness, and quality. Every generic used in Canada has the same medical ingredients as their brand name counterpart and is considered bioequivalent to the brand name medication. The quality standards for brand name drugs and generic drugs are the same. All of the ingredients, facilities, and manufacturing processes must meet Canadian federal guidelines for Good Manufacturing Practices. In addition, Canadian generic manufacturers must perform 'comparative bioavailability' studies to demonstrate that their generic products deliver the same amount of medicinal ingredient at the same rate as the brand name medication. Nearly 45% of all prescriptions filled in Canada use generic medication and some hospitals exclusively use generic drugs. For more information, please visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/med-gen-eng.php
What is Xifaxan?
If you want to buy Xifaxan in Canada or from any canadian pharmacy, it will be called Zaxine. Both Xifaxan and Zaxine are simply different brand names for the same chemical Rifaximin. Xifaxan is an antibiotic, which also possess anti-inflammatory properties, that has been used to treat a variety of infections and ailments. Rifaximin is derived from the class of antibiotics known as Rifamycins.
What makes Xifaxan special is that it is poorly absorbed when taken orally and mainly remains in the gastro-intesinal tract; basically it just kind of passes through you like corn from thanksgiving dinner (sorry but that does make the point). Now it’s natural to question why such poor absorption would make Xifaxan special or even useful at all. Well its a case of one person’s trash is another's treasure; because for people with infections in the gut, it is gold. For example, traverler’s diarrhea, c.difficile, and other gas producing bacteria that can, in part, cause irritable bowel syndrome (IBS) are considered localized infection in the lumen of the intestinal tract where Xifaxan will remain and do its magic. Moreover, Xifaxan has been shown to have anti-microbial effect on bacterial, fungal, and parasitic organisms. Furthermore, there is some evidence of beneficial anti-inflammatory properties when indicated for certain types of hepatic encephalopathies (liver inflammation) and other diverticular diseases. As an antibacterial agent it mainly works by inhibiting DNA-dependent RNA synthesis. Specially, it works by attaching to the beta-subunit of bacterial RNA polymerase, thus interfering with bacterial protein synthesis.
Xifaxan seems very good at targeting, and controlling, gas producing bacteria in the gut, thus reducing associated mucosal inflammation and epithelial dysfunction. It is important to note that Xifaxan has a high bile acid solubility, which seems to focus its actions to the small intestine. Other proposed mechanisms of action include: the inhibition of bacterial translocation across and adherence to the epithelial lining of the intestine, and the attenuation of inflammatory cytokines.
A novel use of Xifaxan to treat autism in children is being tested currently. However, the use of Xifaxan in children has not been studied and is considered off-label use in such trials.
How to use Xifaxan
Xifaxan comes as a 550 mg tablet and is normally taken 2 or 3 times per day orally, depending on what it is used for.
Dosing for parasitic and fungal infection can very significantly and depends on the type of organism.
For liver inflammation no more than 2 doses per day should be taken as there is more chance of systemic absorption in patients with compromised liver function.
In IBS with symptoms of diarrhea a 3 times a day course is taken for 2 weeks and if symptoms improve a second round of treatment can be used if necessary.
More than 2 courses have not been studied. If a dose is missed it should be taken immediately unless it is time for the next dose, then just take the regular dose and do not double up on a dose.
Side-effects of Xifaxan
Since Xifaxin is not readily absorbed by the body it has very little side effects, another reason why it is considered a good drug. Of course, like any drug some people can just have sensitivities and allergic reactions; hence, if you develop any sudden rash or shortness of breath you should always stop the medication and seek medical attention immediately.
Tell your doctor right away if you develop: persistent diarrhea, abdominal or stomach pain/cramping, blood/mucus in your stool.
Xifaxan as mentioned before is called Zaxine in Canada. It is a brand name only medication as there is no generic for this medication in Canada or the United States. If you do find a generic version in another country, we would caution you from buying it as this source would not be approved either the FDA in the USA or our equivalent, Health Canada, in Canada. Being a brand only medication Xifaxan can be very costly.
In the United States 2 tablets per day can cost in excess of $60 daily or almost $2000 per month. Without insurance coverage this cost can put this medication out of range for many patients. Patients often resort to look for coupons for Xifaxan or other online discounts for Xifaxan. Other patients resort to buying Xifaxan online from countries outside of North America, like Turkey, or India, or Singapore, the list goes on. Although the price can be very low cost for Xifaxan, but the quality control concerns that exist when purchasing from non North Ameican countries out-weigh the savings benefit.
When purchasing from a reliable pharmacy in Canada, who only sources their medications from locally authorized wholesalers, the quality control concern is mitigated while there is still considerable savings.
At Canada Cloud Pharmacy we only buy Xifaxan from our Health Canada approved wholesalers in Vancouver. Your medication is guaranteed to ship from our pharmacy in Vancouver. If you need this medication you can now buy Xifaxan from a canadian pharmacy with complete peace of mind.
The above information is for informational purpose only. Always follow your Doctor's advice regarding the usage of your medication.